The role of acetaldehyde in the central effects of ethanol.

Authors :: Quertemont E
Grant KA
Correa M
Arizzi MN
Salamone JD
Tambour S
Aragon CMG
McBride WJ
Rodd ZA
Goldstein A
Zaffaroni A
Li T
Pisano M
Diana M
Source :: Alcoholism: Clinical & Experimental Research. Feb2005, Vol. 29 Issue 2, p221-234. 14p.
Publication Year :: 2005
Abstract: This article represents the proceedings of a symposium at the 2004 annual meeting of the Research Society on Alcoholism in Vancouver, Canada. The symposium was organized by Etienne Quertemont and chaired by Kathleen A. Grant. The presentations were (1) Behavioral stimulant effects of intracranial injections of ethanol and acetaldehyde in rats, by Merce Correa, Maria N. Arizzi and John D. Salamone; (2) Behavioral characterization of acetaldehyde in mice, by Etienne Quertemont and Sophie Tambour; (3) Role of brain catalase and central formed acetaldehyde in ethanol's behavioral effects, by Carlos M.G. Aragon; (4) Contrasting the reinforcing actions of acetaldehyde and ethanol within the ventral tegmental area (VTA) of alcohol-preferring (P) rats, by William J. McBride, Zachary A. Rodd, Avram Goldstein, Alejandro Zaffaroni and Ting-Kai Li; and (5) Acetaldehyde increases dopaminergic transmission in the limbic system, by Milena Pisano and Marco Diana. [ABSTRACT FROM AUTHOR]