Generation of immunostimulatory dendritic cells from the malignant clone in patients with juvenile myelomonocytic leukemia.

Authors :: Nabarro, S.
Thrasher, A.J.
Kempski, H.
Amrolia, P.
Anderson, J.
Source :: Leukemia (08876924). Sep2003, Vol. 17 Issue 9, p1910. 3p.
Publication Year :: 2003
Abstract: Describes the generation of immunostimulatory dendritic cells from the malignant clone in patients with juvenile myelomonocytic leukemia. Induction of anti-leukemia T cell responses; Measurement of the dendritic cell production of interleukin-2; Reflection of the heterogeneity of myeloid lineage leukemia; Characteristics of immature dendritic cell morphology.

Subjects :: *DENDRITIC cells
*MYELOID leukemia
*IMMUNOLOGICAL adjuvants
*INTERLEUKIN-2
*T cells

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