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Diastereoselective synthesis of anti-3-hydroxy-2-trifluoromethyl carboxylic acids.
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Jun2015, Vol. 56 Issue 23, p3019-3022. 4p. - Publication Year :
- 2015
-
Abstract
- Unlike the hydrocarbon analogs, this first report of enolboration–aldolization of 3,3,3-trifluoropropanoic acid provides essentially pure anti -diastereomers of α-trifluoromethyl-β-hydroxy carboxylic acids in 77–90% yields. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 56
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 108292553
- Full Text :
- https://doi.org/10.1016/j.tetlet.2014.12.045