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Ribo-, Xylo-, and Arabino-Configured Adenine-Based Nucleoside Phosphonates: Synthesis of Monomers for Solid-Phase Oligonucleotide Assembly.
- Source :
-
Nucleosides, Nucleotides & Nucleic Acids . May2003, Vol. 22 Issue 5-8, p1053-1056. 4p. - Publication Year :
- 2003
-
Abstract
- Adenine-based, regioisomeric nucleoside phosphonates with ribo, xylo and arabino configuration were synthesized in the protected form suitable for the phosphotriester-like, solid-phase synthesis of oligonucleotides. Phosphonate moiety was protected by 4-methoxy-1-oxido-2-picolyl group and the furanose hydroxyl by the dimethoxytrityl group. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NUCLEOSIDES
*PHOSPHONIC acids
*ADENOSINES
*OLIGONUCLEOTIDES
*HYDROXYL group
Subjects
Details
- Language :
- English
- ISSN :
- 15257770
- Volume :
- 22
- Issue :
- 5-8
- Database :
- Academic Search Index
- Journal :
- Nucleosides, Nucleotides & Nucleic Acids
- Publication Type :
- Academic Journal
- Accession number :
- 10833776
- Full Text :
- https://doi.org/10.1081/NCN-120022734