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Immunoglobulin G4-Related Disease in the Head and Neck: Two Case Reports and Literature Review.
- Source :
-
Archives of Rheumatology . 2015, Vol. 30 Issue 2, p172-177. 6p. 2 Black and White Photographs. - Publication Year :
- 2015
-
Abstract
- Immunoglobulin G4-related disease (IgG4-related disease) is a fibroinflammatory disorder defined by elevated serum IgG4 level and plasma cells tissue infiltration accompanied by fibrosis or sclerosis. In this article, we report two patients of IgG4 syndrome: a 60-year-old male with complaints of nasal congestion, rhinitis, anosmia and hearing loss, and a 28-year-old female with bilateral orbital and parotid gland swelling. Histopathological findings and high serum IgG4 level confirmed diagnosis of IgG4-related disease. Both patients were treated successfully with glucocorticoids and methotrexate. Herein, we also review clinical presentations of IgG4-related disease in head and neck, and related diagnostic and therapeutic approach. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 21485046
- Volume :
- 30
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Archives of Rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 108438020
- Full Text :
- https://doi.org/10.5606/ArchRheumatol.2015.5105