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The comparison of plasma D-dimer levels in benign and malignant tumors of cervix, ovary and uterus.
- Source :
-
International Journal of Hematology-Oncology & Stem Cell Research . 7/1/2015, Vol. 9 Issue 3, p107-111. 5p. - Publication Year :
- 2015
-
Abstract
- Background: Thromboembolism is the most important complication of cancers. The aim of this study was to determine D-dimer levels in benign and malignant tumors of the uterus, ovary and cervix. Subjects and Methods: This was a cross sectional study and it was conducted on 90 female patients referred to Imam Khomeini and Arash Hospitals because of uterine, cervical and ovarian tumors in 2013-2014. After surgical resection or tissue biopsy, 2 cc of each patient's blood was taken to be sent to laboratory of hospitals. "Nycocard" kit was chosen to measure D-dimer levels in Mg/Lit by neflumetry method. Data were analyzed in SPSS-16 by T-test and One-Way ANOVA test. Results: The highest mean of D-dimer was 3.9 (± 2.9SD) in malignant cervical tumors. The mean plasma levels of D-dimer in malignant uterine cancers (P = 0.008), ovarian cancers (P = 0.007) and cervical cancers (P = 0.006) was significantly higher than benign tumors. In all three types of uterine, ovarian and cervical cancers, D-dimer was significantly higher in advanced stages than lower stages. Conclusion: The plasma D-dimer levels in patients with malignant tumors of the uterus, cervix and ovary were higher than benign types. By increasing the stage of gynecologic malignant tumors, the levels of plasma D-dimer were increased. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20083009
- Volume :
- 9
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- International Journal of Hematology-Oncology & Stem Cell Research
- Publication Type :
- Academic Journal
- Accession number :
- 108526650