daf-41/p23: A Small Protein Heating Up Lifespan Regulation.

The author presents information on daf-41/p23 which is a small protein heating up lifespan regulation. He says that the daf-21 allele p673 represents a mutation in the heat shock protein HSF-1 which was considered to cause constitutive dauer entry. He adds that the general regulator of the heat shock response HSF-1 influences the life span in coordination with other dauer genes and its depletion results in early onset of aging.