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Bioactive triterpenoids from Atriplex lasiantha.
- Source :
-
Journal of Asian Natural Products Research . Aug2015, Vol. 17 Issue 8, p843-850. 8p. - Publication Year :
- 2015
-
Abstract
- Chromatographic purification of the ethyl acetate soluble fraction from the methanolic extract ofAtriplex lasianthayielded a new triterpenoid, 7β,15α,16β-trihydroxyolean-12-ene-28,30-dioic acid-3-O-β-d-xylopyranoside (1), along with two known triterpenoids, rotundifolioside I (2) and corchorusin B (3). Structures of the compounds1–3were elucidated through sophisticated NMR studies and high resolution mass spectrometry. The three isolates (1–3) were evaluated for antibacterial, antioxidant, and antiurease activities. Compound2exhibited the best antibacterial activity againstEscherichiacoliwith IC50value of 66.25 μg/ml, whereas, all the tested compounds exhibited antioxidant (IC50values of 68.7–75.4 μg/ml) and antiurease (IC50values of 25.5–49.3 μg/ml) activities, respectively. [ABSTRACT FROM PUBLISHER]
- Subjects :
- *ANTIBIOTICS assay
*ANTIOXIDANT analysis
*BACTERIA
*BIOLOGICAL assay
*CHROMATOGRAPHIC analysis
*ESCHERICHIA coli
*FREE radicals
*INFRARED spectroscopy
*MASS spectrometry
*MOLECULAR structure
*NUCLEAR magnetic resonance spectroscopy
*TERPENES
*UREA
*UREASE
*VITAMIN C
*PLANT extracts
*AMPICILLIN
*DATA analysis software
*DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 17
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 108840784
- Full Text :
- https://doi.org/10.1080/10286020.2015.1008463