Back to Search
Start Over
Electrophilic N-Trifluoromethylation of N-H Ketimines.
- Source :
-
Journal of Organic Chemistry . 9/4/2015, Vol. 80 Issue 17, p8910-8915. 6p. - Publication Year :
- 2015
-
Abstract
- A direct N-trifluoromethylation method has been developed by the use of the in situ generated [ArICF3]+ species as the electrophilic trifluoromethyl source. Upon treatment of N-H ketimines with Ruppert-Prakash reagent in the presence of PhI(OAc)2 and KF, or with Togni's reagent II catalyzed by copper salt, N-trifluoromethylated imine products were obtained in moderate to good yields. [ABSTRACT FROM AUTHOR]
- Subjects :
- *METHYLATION
*ALKYLATION
*IMINES
*ORGANONITROGEN compounds
*IMINO group
Subjects
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 80
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 109564106
- Full Text :
- https://doi.org/10.1021/acs.joc.5b01468