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Short-term effect of the combination of hyaluronic acid, chondroitin sulfate, and keratin matrix on early symptomatic knee osteoarthritis.
- Source :
-
European Journal of Rheumatology . Sep2015, Vol. 2 Issue 3, p106-108. 3p. - Publication Year :
- 2015
-
Abstract
- Objective: In the last years, symptomatic slow-acting drugs for osteoarthritis (SYSADOA) have been vastly studied and have generated considerable interest among clinicians. SYSADOA are generally used as a ground therapy with the main rationale to reduce the consumption of nonsteroidal anti-inflammatory drugs (NSAIDs)and thus limit the related adverse events. Material and Methods: In this study, we evaluated the short-term effect of an oral combination of hyaluronic acid, chondroitin sulfate, and keratin matrix on early symptomatic knee osteoarthritis. Forty patients were treated for 1 month and were allowed to assume analgesics or NSAIDs if necessary. Results: At 2 months, the mean reduction of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score was 36% (p<0.001), and the mean reduction of the WOMAC pains score was 40% (p<0.001). Only two patients reported a sporadic need to assume analgesics; no patient reported any side effect during the study period. Conclusion: This data demonstrates that the oral combination of hyaluronic acid, chondroitin sulfate, and keratin matrix is safe, well tolerated, and shows a rapid action reducing pain and i m proving joint function and stiffness in early symptomatic knee osteoarthritis. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 21484279
- Volume :
- 2
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- European Journal of Rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 110011118
- Full Text :
- https://doi.org/10.5152/eurjrheum.2015.0019