Letter to the editor P301L Tau mutation and non-Alzheimer dementias in Italy.

Focuses on the breakthrough in medical science research which reveals that mutations in the tau gene are responsible for familial fronto-temporal dementia (FTD), progressive supranuclear palsy (PSP) and cortico-basal degeneration (CBD). Revelation that Proline-to-Leucine mutation at codon 301 is the most common tau mutation in FTD; Details of the study conducted in Italy to assess the frequency of Proline-to-Leucine mutation; Information on the type of patients selected for the study.