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A comparison of PGC-1α mRNA and protein expression in response to 1-week endurance training on alternate days or 4 consecutive days.
- Source :
-
Applied Physiology, Nutrition & Metabolism . Nov2015, Vol. 40 Issue 11, p1210-1213. 4p. 1 Chart, 2 Graphs. - Publication Year :
- 2015
-
Abstract
- To understand the molecular mechanisms of adaptation to different training protocols, this study compared the effects of 4 sessions of 90 min treadmill exercise on alternate days or consecutive days in 1 week on messenger RNA (mRNA) and protein expression of proliferator-activated receptor-γ coactivator 1-α in rat gastrocnemius muscle. The mRNA significantly increased by 25.8-fold after alternate-day and 10.1-fold after consecutive-day training, while the protein showed no significant cumulative effect, 1.5-1.7-fold above baseline, in the 2 protocols. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MUSCLE proteins
*CALF muscle physiology
*RNA analysis
*AGAR
*ANIMAL experimentation
*ELECTROPHORESIS
*GENE expression
*RESEARCH methodology
*PHYSICAL fitness
*POLYMERASE chain reaction
*PROBABILITY theory
*RATS
*RESEARCH funding
*STATISTICAL sampling
*SPECTROPHOTOMETRY
*STATISTICS
*DATA analysis
*TREADMILLS
*DATA analysis software
*DESCRIPTIVE statistics
*ONE-way analysis of variance
*PHYSIOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 17155312
- Volume :
- 40
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Applied Physiology, Nutrition & Metabolism
- Publication Type :
- Academic Journal
- Accession number :
- 110605492
- Full Text :
- https://doi.org/10.1139/apnm-2015-0222