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Natural Killer Cell Memory.

Authors :
O’Sullivan, Timothy E.
Sun, Joseph C.
Lanier, Lewis L.
Source :
Immunity (10747613). Oct2015, Vol. 43 Issue 4, p634-645. 12p.
Publication Year :
2015

Abstract

Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond against pathogens and tumors in an antigen-independent manner and then undergo cell death. Recently, however, NK cells have been shown to possess traits of adaptive immunity and can acquire immunological memory in a manner similar to that of T and B cells. In this review, we discuss evidence of NK cell memory and the mechanisms involved in the generation and survival of these innate lymphocytes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10747613
Volume :
43
Issue :
4
Database :
Academic Search Index
Journal :
Immunity (10747613)
Publication Type :
Academic Journal
Accession number :
110680115
Full Text :
https://doi.org/10.1016/j.immuni.2015.09.013