Back to Search Start Over

BCG IMMUNISATION IMPAIRS VASCULAR RELAXATION AND EXCHANGES ATHEROSCLEROSIS IN THE CHRONICALLY HYPERCHOLESTEROLAEMIC RABBIT.

Authors :
Tickner, M. L.
Lamb, D. J.
Dreux, A. C.
El-Sankary, W.
Hourani, S. M. O.
Eales-Reynolds, L-J
Ferns, G. A. A.
Source :
British Journal of Pharmacology. Sep2003 Supplement, Vol. 140, p36P-36P. 1/2p.
Publication Year :
2003

Abstract

Investigates the relationship between anti-heat shock protein-60/65 (HSP) immune responses, endothelial dysfunction and atherosclerosis in the chronic low-level hypercholesterolaemic rabbit model using the Calmette-Guerin (BCG) immunization. Rise in plasma level of mycobacterial antibodies after BCG immunization; Impaired endothelial response and increased atherosclerosis due to BCG immunization; Mediation by immune response against mycobacterial and vascular HSP.

Subjects

Subjects :
*HEAT shock proteins
*IMMUNE response
*BCG vaccines
*ATHEROSCLEROSIS
*ANIMAL experimentation

Details

Language :
English
ISSN :
00071188
Volume :
140
Database :
Academic Search Index
Journal :
British Journal of Pharmacology
Publication Type :
Academic Journal
Accession number :
11099213

Tools

Authors Abstract Subjects Details