One-Step Synthesis of Alkyl 2-Chloropyrimido[1,2-a]benzimidazole-3-carboxylates under Catalyst-Free: Combined Experimental and Computational Studies.

The title species (IV) are prepared through a facile one-pot reaction of substrates (I) and (II) with alcohols. The yield goes down with increased steric hinderance of the alcohol. Thus, isopropanol and tert-butanol give only traces of the target products. [ABSTRACT FROM AUTHOR]