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Combining C6 and C5 sugar metabolism for enhancing microbial bioconversion.
- Source :
-
Current Opinion in Chemical Biology . Dec2015, Vol. 29, p49-57. 9p. - Publication Year :
- 2015
-
Abstract
- Mixed sugars, which are often obtained from renewable biomass, can be converted into biofuels and chemicals by microbial conversion. This sustainable production process can also mitigate man-made climate change when used to petroleum-based fuel and chemical production. In contrast to single sugar fermentations, such as corn-based or sugarcane-based ethanol fermentations, mixed sugar fermentations present significant challenges for cost-effective production of the target products. In particular, inefficient and slow microbial fermentation of non-glucose sugars, such as galactose and xylose from the depolymerization of marine and terrestrial biomass has been a major obstacle. Nonetheless, simultaneous utilization of mixed sugars has recently been demonstrated through innovative metabolic engineering strategies and the discovery of transporters, and metabolic pathways which are necessary for co-fermenting glucose and non-glucose sugars. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13675931
- Volume :
- 29
- Database :
- Academic Search Index
- Journal :
- Current Opinion in Chemical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 111498682
- Full Text :
- https://doi.org/10.1016/j.cbpa.2015.09.008