In early HIV infection, immediate vs deferred antiretroviral therapy reduced serious illnesses at 3 years.

The article discusses reduction in serious AIDS-related or non-AIDS-related illnesses in early HIV infection by immediate antiretroviral therapy (ART) as compared to deferred ART. Topics discussed include establishing criteria for treatment based delivering HIV care, endorsing treatment regardless of CD4+ count by HIV guidelines and prevention of tuberculosis (TB) by Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis against Tuberculosis in HIV-infected Adults (TEMPRANO) trials.