Structural and spectroscopic investigation on a new potentially bioactive di-hydrazone containing thiophene heterocyclic rings.

Hydrazones and several substituted hydrazones are associated with a broad spectrum of biological activities, as well as compounds containing the thiophene ring. In this context, a novel di-hydrazone derived from 2-thiophenecarboxylic acid hydrazide was synthesized and completely characterized by elemental analysis, XRD, FT-IR, Raman and UV–Vis spectroscopies, thermogravimetry, 1 H NMR, 1 H– 1 H COSY and 1 H– 1 H ROESY. A preliminary in silico pharmacological evaluation was also performed in order to assess the performance of the new compound regarding some molecular properties relevant for a drug's pharmacokinetics in the human body. [ABSTRACT FROM AUTHOR]