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Late detection of cleft palate.

Authors :
Hanny, K.
Vries, I.
Haverkamp, S.
Oomen, K.
Penris, W.
Eijkemans, M.
Kon, M.
Mink van der Molen, A.
Breugem, C.
Hanny, K H
de Vries, I A C
Haverkamp, S J
Oomen, K P Q
Penris, W M
Eijkemans, M J C
Mink van der Molen, A B
Breugem, C C
Source :
European Journal of Pediatrics. Jan2016, Vol. 175 Issue 1, p71-80. 10p. 1 Diagram, 5 Charts, 1 Graph.
Publication Year :
2016

Abstract

<bold>Unlabelled: </bold>Cleft palate only (CPO) is a common congenital malformation, and most patients are diagnosed within the first weeks after birth. Late diagnosis of the cleft palate (CP) could initially result in feeding and growth impairment, and subsequently speech and hearing problems later in life. The purpose of this study is to retrospectively investigate (1) at which age CPO is diagnosed and (2) how the presence of syndromes and other factors relate to the age at diagnosis. The mean age of all children at our centre with CPO included between 1997 and 2014 at diagnosis (n = 271) was 1 year and 4 months. In all, 24.8% (n = 67) was older than 12 months when diagnosed, and 37.3% (n = 101) of all children had been diagnosed >30 days. These findings remain valid when a cut-off point of 14 days is used (44.3% late). Moreover, the grade of the cleft was a determining factor for successful diagnosis; submucous clefts were detected much later on average (89.3% > 30 days; p = .000). Similar results were found using Kaplan-Meier survival analyses.<bold>Conclusion: </bold>CPO is often diagnosed late. Patients diagnosed ≤30 days after birth more often presented with an associated disorder. Early diagnoses became more frequent as the severity of the cleft increased (grades 1-4). Professionals should perform more thorough intra-oral investigations, including manual palpations and visual inspections of the palate; they should be made more aware of the frequent accompanying symptoms.<bold>What Is Known: </bold>The presence of cleft palate only (CPO) is known to negatively affect feeding, hearing, speech and (social) development. Submucous clefts are often underdiagnosed due to their difficulty to detect. As far as we know the literature shows that symptomatic submucous CPs are often diagnosed at an average age of 4.9 years.<bold>What Is New: </bold>37.3% respectively of all children with CPO were diagnosed relatively late (>30 days after birth), 24.8% was older than 12 months when diagnosed. Mean age of all children with CPO was 1 year and 4 months. We conclude that midwives and pediatricians should perform more through intra-oral investigations of all new-borns, including both a manual palpation, als well a visual inspection of the palate. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03406199
Volume :
175
Issue :
1
Database :
Academic Search Index
Journal :
European Journal of Pediatrics
Publication Type :
Academic Journal
Accession number :
112212893
Full Text :
https://doi.org/10.1007/s00431-015-2590-9