Back to Search
Start Over
Implications and issues related to familial pancreatic cancer: a cohort study of hospitalized patients.
- Source :
-
BMC Gastroenterology . 1/15/2016, Vol. 16, p1-5. 5p. 1 Diagram. - Publication Year :
- 2016
-
Abstract
- <bold>Background: </bold>The surveillance of subjects at risk of pancreatic cancer is restricted to clinical research; the incidence of familial pancreatic cancer needs to be better established. Thus, we aimed to evaluate the frequency of familial pancreatic cancer in a population of hospitalized patients with pancreatic cancer.<bold>Methods: </bold>A retrospective study based on the hospital charts of patients discharged with a diagnosis of pancreatic cancer. One hundred and eighty-seven patients or their relatives were called for a phone interview.<bold>Results: </bold>There were 97 males (51.9 %) and 90 (48.1 %) females. The overall mean ± SD age was 67.3 ± 11.8 years; the age of males was similar to that of females (P = 0140). The mean size of the tumors found was 36.3 ± 17.4 mm (range of 5-110 mm); it was related to gender but was not related to the site of the tumor or the age of the patient. Regarding genetic diseases, three females (1.6 %) had familial adenomatous polyposis; three patients (1 male and two females) (1.6 %) had at least one relative with pancreatic cancer whereas only one 80-year old male patient (0.5 %) had two relatives affected by pancreatic cancer (the mother had died at the 65 years of age and the brother had died at 75 years of age).<bold>Conclusions: </bold>The frequency of familial pancreatic ductal adenocarcinoma is small, but its importance, from the point of view of early diagnosis, is not negligible and patients with a risk of familial cancer merit an appropriate clinical follow-up. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PANCREATIC cancer diagnosis
*PANCREATIC cancer treatment
*PANCREATIC cancer genetics
*ADENOMATOUS polyposis coli
*CANCER patients
*EPIDEMIOLOGY of cancer
*ADENOCARCINOMA
*AGE distribution
*CANCER
*DISEASE susceptibility
*HOSPITAL care
*PANCREATIC tumors
*SEX distribution
*DISEASE incidence
*RETROSPECTIVE studies
*DUCTAL carcinoma
Subjects
Details
- Language :
- English
- ISSN :
- 1471230X
- Volume :
- 16
- Database :
- Academic Search Index
- Journal :
- BMC Gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 112319029
- Full Text :
- https://doi.org/10.1186/s12876-016-0421-8