A green four-component synthesis of 2-amino-3-cyano-4-aryl-6-sulfanepyrimidine in water solvent using phase-transfer catalyst.

Authors :: Xu, Liang
Gu, Chenghao
Li, Rou
Yu, Yikai
Wang, Tao
Source :: Journal of the Iranian Chemical Society. Apr2016, Vol. 13 Issue 4, p597-604. 8p.
Publication Year :: 2016
Abstract: New green one-pot four-component reactions of thiourea, malononitrile halohydrocarbon, aldehydes and alkyl halide have been successfully developed in eco-friendly water solvent through available phase-transfer catalyst, to access high yields of 2-amino-3-cyano-4-aryl-6-sulfanepyrimidines. [ABSTRACT FROM AUTHOR]

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