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Silver-Mediated Intermolecular 1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles.
- Source :
-
Angewandte Chemie . Feb2016, Vol. 128 Issue 9, p3239-3243. 5p. - Publication Year :
- 2016
-
Abstract
- A new iron-facilitated silver-mediated radical 1,2-alkylarylation of styrenes with α-carbonyl alkyl bromides and indoles is described, and two new C−C bonds were generated in a single step through a sequence of intermolecular C(sp3)−Br functionalization and C(sp2)−H functionalization across the alkenes. This method provides an efficient access to alkylated indoles with broad substrate scope and excellent selectivity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ALKYL bromides
*INDOLE compounds
*INTERMOLECULAR interactions
*ALKENES
Subjects
Details
- Language :
- English
- ISSN :
- 00448249
- Volume :
- 128
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Angewandte Chemie
- Publication Type :
- Academic Journal
- Accession number :
- 113001572
- Full Text :
- https://doi.org/10.1002/ange.201511624