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Enantioselective Synthesis of Tetrahydroindolizines via RutheniumChiral Phosphoric Acid Sequential Catalysis.
- Source :
-
Synlett . 2016, Vol. 27 Issue 4, p586-590. 5p. - Publication Year :
- 2016
-
Abstract
- A chiral phosphoric acid and a ruthenium complex were found to catalyze an olefin cross-metathesis-asymmetric intramolecular Friedel-Crafts alkylation of N-tethered olefin pyrroles and conjugated enones to provide a variety of chiral tetrahydroindolizine derivatives in moderate to good yields and enantioselectivity (up to 93% ee). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09365214
- Volume :
- 27
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Synlett
- Publication Type :
- Academic Journal
- Accession number :
- 113146474
- Full Text :
- https://doi.org/10.1055/s-0035-1560485