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M-Dinitroaromatic Moiety as a Fragment of Biologically Active Compounds.

Authors :
Piskov, V.
Chernyshev, V.
Karakotov, S.
Source :
Pharmaceutical Chemistry Journal. Feb2016, Vol. 49 Issue 11, p724-734. 11p.
Publication Year :
2016

Abstract

Data on the biological activities of compounds containing m-dinitroaromatic ( m-DAr) moieties were presented and led to the conclusion that including this moiety in the structures of new biologically active compounds was promising. It was established that one nitro group in m-DAr could be replaced by trifluoromethyl without losing the biological activity of the obtained analogs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0091150X
Volume :
49
Issue :
11
Database :
Academic Search Index
Journal :
Pharmaceutical Chemistry Journal
Publication Type :
Academic Journal
Accession number :
113220954
Full Text :
https://doi.org/10.1007/s11094-016-1361-x