Two new peroxy fatty acids with antibacterial activity from Ophioglossum thermale Kom.

Two new peroxy fatty acids, thermalic acids A ( 1 ) and B ( 2 ), together with eight known compounds, (3 β )-methyl-3-hydroxy-urs-11-en-28 oate ( 3 ), luteolin ( 4 ), quercetin ( 5 ), 3-methoxyquercetin ( 6 ), ophioglonol ( 7 ), ophioglonol 4′-O- α -D-glucopyranoside ( 8 ), pedunculosumoside B ( 9 ), syringol ( 10 ), were isolated from the herba of Ophioglossum thermale Kom. The structures of 1 and 2 were identified by HRESIMS, EIMS, 1D and 2D NMR, and electronic circular dichroism (ECD) spectra. Both two acids exhibited potential antibacterial activities against Staphylococcus aureus , Bacillus subtilis , and Escherichia coli . This is the first report of peroxy fatty acids isolated from herbaceous plants of Ophioglossaceae. [ABSTRACT FROM AUTHOR]