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PET/MRI with diagnostic MR sequences vs PET/CT in the detection of abdominal and pelvic cancer.
- Source :
-
European Journal of Radiology . Apr2016, Vol. 85 Issue 4, p751-759. 9p. - Publication Year :
- 2016
-
Abstract
- <bold>Objective: </bold>Integrated positron emission tomography/magnetic resonance imaging (PET/MRI) scanners provide combined MR-based anatomic and metabolic image information. The aim of this study was to evaluate qualitative and quantitative diagnostic performance of PET/MR with (18)fluoro-2-deoxyglucose ((18)F-FDG) using a diagnostic MR sequence in patients with abdominal and pelvic tumors, compared to positron emission tomography/computed tomography (PET/CT). <bold>Materials and Methods: </bold>Forty five patients underwent a single-injection ((18)F-FDG), dual-imaging protocol including whole-body PET/CT and subsequent regional PET/MR hybrid imaging. A regional PET/MR scan followed the PET/CT. Images from both modalities were analyzed using a 3-point scale for PET/CT and PET/MR image quality, image alignment, and lesion visibility on PET images. PET-CT/PET-MR functional and anatomical correlation was analyzed. <bold>Results: </bold>A total of 66 lesions were studied, from which 63 were identified using PET/CT and 59 were identified using PET/MR. The (18)F-FDG PET images had good diagnostic quality (P<0.001); alignment was found to be excellent in PET/MR data as well as PET/CT data (P=0.102), and there was no difference in lesion visibility (P=0.18). The average rating score regarding anatomical correlation for PET-positive lesions was 2.75 for combined MR sequence images and 2.04 for CT, with a significant difference (P=0.317), Standard uptake value (SUV) for focal lesions had excellent correlation (SUVmax/mean: R=0.948/0.948); furthermore, the SUVmean of background organs combined, bone marrow and the muscle tissue showed good correlation (R=0.329/0.398/0.298). No correlations were found in the liver and spleen. <bold>Conclusions: </bold>PET/MR with diagnostic MR sequence was able to detect abdominal and pelvic lesions and had good image quality compared to PET/CT. SUVmax and SUVmean values in focal lesions, and the SUVmean of background organs generally correlated well in abdominal and pelvic oncology patients examined using PET/CT and PET/MRI. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CANCER diagnosis
*STOMACH cancer
*MAGNETIC resonance imaging of cancer
*CANCER tomography
*POSITRON emission tomography
*FLUORODEOXYGLUCOSE F18
*DIAGNOSIS
*ABDOMINAL tumors
*COMPUTED tomography
*DEOXY sugars
*DIAGNOSTIC imaging
*DIGITAL image processing
*LONGITUDINAL method
*MAGNETIC resonance imaging
*RADIOPHARMACEUTICALS
PELVIS cancer
PELVIC tumors
Subjects
Details
- Language :
- English
- ISSN :
- 0720048X
- Volume :
- 85
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- European Journal of Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 113666837
- Full Text :
- https://doi.org/10.1016/j.ejrad.2016.01.010