Back to Search
Start Over
Symptom burden in long-term germ cell tumor survivors.
- Source :
-
Supportive Care in Cancer . May2016, Vol. 24 Issue 5, p2243-2250. 8p. - Publication Year :
- 2016
-
Abstract
- <bold>Purpose: </bold>Testicular germ cell tumor (GCT) and its treatment may cause distressing long-term symptoms. We aimed to examine self-reported symptom frequency and distress as well as the impact of demographic and medical characteristics in GCT survivors.<bold>Methods: </bold>A total of 164 GCT survivors receiving follow-up care at the University Cancer Center Hamburg and a specialized private practice facility were interviewed at a median time of 11.6 years after first diagnosis. Metastatic disease was present in 48 % of the patients and relapse had occurred in 17 %. The patients completed the short form of the Memorial Symptom Assessment Scale (MSAS-SF) assessing 28 physical and 4 psychological symptoms.<bold>Results: </bold>The mean number of physical symptoms was 4.5 (SD = 4.3) (psychological symptoms M = 1.4, SD = 1.4; total M = 5.9, SD = 5.2). The most frequent physical symptoms were lack of energy (49 %), feeling drowsy (42 %), sleeping problems (36 %), and difficulty in concentration (32 %). Lack of energy was experienced as highly distressing by 21 % of the patients. The most frequent psychological symptoms were irritability (47 %) and being worried (42 %). The number of physical symptoms was associated with higher age, lower socioeconomic status, and shorter time since diagnosis in multivariate regression analyses controlling for metastatic vs. localized disease, relapse, extent of surgery, number of chemotherapy cycles, and radiotherapy.<bold>Conclusions: </bold>GCT survivors suffered from a significant number of long-term symptoms. Fatigue-related symptoms were most frequent and perceived as highly distressing. Continuous attention toward fatigue is necessary throughout follow-up care to offer support in time, particularly in more vulnerable patients of higher age and lower socioeconomic status. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GERM cell tumors
*TESTICULAR cancer treatment
*SYMPTOMS
*PSYCHOLOGICAL distress
*FATIGUE (Physiology)
*SOCIOECONOMIC factors
*HEALTH of cancer patients
*TUMOR treatment
*COMPARATIVE studies
*RESEARCH methodology
*MEDICAL cooperation
*RESEARCH
*PSYCHOLOGICAL stress
*EVALUATION research
*TESTIS tumors
*PSYCHOLOGICAL factors
*DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 09414355
- Volume :
- 24
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Supportive Care in Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 113946206
- Full Text :
- https://doi.org/10.1007/s00520-015-3026-9