Borylation of Olefin C-H Bond via Aryl to Vinyl Palladium 1,4- Migration.

Authors :: Tian-Jiao Hu
Ge Zhang
Ya-Heng Chen
Chen-Guo Feng
Guo-Qiang Lin
Source :: Journal of the American Chemical Society. 3/9/2016, Vol. 138 Issue 9, p2897-2900. 4p.
Publication Year :: 2016
Abstract: The aryl to vinyl palladium 1,4-migration was realized for the first time. The generated alkenyl palladium species was trapped by diboron reagents under Miyaura borylation conditions, providing a new method to synthesize ββ-disubstituted vinylboronates. The excellent regioselectivity and broad substrate scope were observed for this novel transformation. [ABSTRACT FROM AUTHOR]