Back to Search
Start Over
Evaluating Physical Outcomes in Acute Respiratory Distress Syndrome Survivors: Validity, Responsiveness, and Minimal Important Difference of 4-Meter Gait Speed Test.
- Source :
-
Critical Care Medicine . May2016, Vol. 44 Issue 5, p859-868. 10p. - Publication Year :
- 2016
-
Abstract
- <bold>Objective: </bold>To examine the reliability, validity, responsiveness, and minimal important difference of the 4-m gait speed test in acute respiratory distress syndrome survivors.<bold>Design: </bold>Secondary analyses of data from two longitudinal follow-up studies of acute respiratory distress syndrome survivors. Test-retest and inter-rater reliability, construct validity (convergent, discriminant, and known group), predictive validity, and responsiveness were examined. The minimal important difference was estimated using anchor- and distribution-based approaches.<bold>Setting: </bold>A national multicenter prospective study (ARDSNet Long-Term Outcome Study) and a multisite prospective study in Baltimore, MD (Improving Care of Acute Lung Injury Patients).<bold>Patients: </bold>Acute respiratory distress syndrome survivors with 4-m gait speed assessment up to 60 months after acute respiratory distress syndrome (ARDSNet Long-Term Outcome Study, n = 184; Improving Care of Acute Lung Injury Patients, n = 122).<bold>Interventions: </bold>Not applicable.<bold>Measurements and Main Results: </bold>Four-meter gait speed was assessed at 6- and 12-month follow-up (ARDSNet Long-Term Outcome Study) and 36-, 48-, and 60-month follow-up (Improving Care of Acute Lung Injury Patients). Excellent test-retest (intraclass correlation, 0.89-0.99 across studies and follow-up) and inter-rater (intraclass correlation, 0.97) reliability were found. Convergent validity was supported by moderate-to-strong correlations (69% of 32 > 0.40) with other physical function measures. Discriminant validity was supported by weak correlations (86% of 28 < 0.30) with mental health measures. Survivors with impaired versus nonimpaired measures of muscle strength and pulmonary function had significantly slower 4-m gait speed (all but one p < 0.05). Furthermore, 4-m gait speed significantly predicted future hospitalization and health-related quality of life. Gait speed changes were consistent with reported changes in function, supporting responsiveness. The estimated 4-m gait speed minimal important difference was 0.03-0.06 m/s.<bold>Conclusions: </bold>The 4-m gait speed is a reliable, valid, and responsive measure of physical function in acute respiratory distress syndrome survivors. The estimated minimal important difference will facilitate sample size calculations for clinical studies evaluating the 4-m gait speed test in acute respiratory distress syndrome survivors. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ADULT respiratory distress syndrome
*PULMONARY manifestations of general diseases
*INTRACLASS correlation
*PSYCHOMETRICS
*TEST validity
*COMPARATIVE studies
*GAIT in humans
*LONGITUDINAL method
*RESEARCH methodology
*MEDICAL cooperation
*QUALITY of life
*RESEARCH
*RESEARCH funding
*COMORBIDITY
*EVALUATION research
*PREDICTIVE tests
*RESEARCH bias
*SEVERITY of illness index
RESEARCH evaluation
Subjects
Details
- Language :
- English
- ISSN :
- 00903493
- Volume :
- 44
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Critical Care Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 114547636
- Full Text :
- https://doi.org/10.1097/CCM.0000000000001760