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2,6-Bis(benzimidazol-2-yl)pyridine as a potent transmembrane anion transporter.

Authors :
Peng, Chen-Chen
Li, Zhi
Deng, Li-Qun
Ke, Zhuo-Feng
Chen, Wen-Hua
Source :
Bioorganic & Medicinal Chemistry Letters. May2016, Vol. 26 Issue 10, p2442-2445. 4p.
Publication Year :
2016

Abstract

2,6-Bis(benzimidazol-2-yl)pyridine was shown to exhibit potent anionophoric activity via a process of both Cl − /NO 3 − antiport and H + /Cl − symport. This is in sharp contrast to the finding that its corresponding N -methylated analog exhibited negligible activity and reveals the importance of the imidazolyl-N H fragments in the anion-transport process. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0960894X
Volume :
26
Issue :
10
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
114628654
Full Text :
https://doi.org/10.1016/j.bmcl.2016.03.114