ChemInform Abstract: An N-Heterocyclic Carbene-Catalyzed Oxidative γ-Aminoalkylation of Saturated Carboxylic Acids Through in situ Activation Strategy: Access to δ-Lactam.

Authors :: Que, Yonglei
Xie, Yuanwei
Li, Tuanjie
Yu, Chenxia
Tu, Shujiang
Yao, Changsheng
Source :: ChemInform. Apr2016, Vol. 47 Issue 19, pno-no. 1p.
Publication Year :: 2016
Abstract: A series of chiral δ-lactams (III) and (V) is prepared with high enantioselectivity by NHC-catalyzed oxidative γ-aminoalkylation of carboxylic acids (II) with acylhydrazones. [ABSTRACT FROM AUTHOR]

Subjects :: *HETEROCYCLIC compound derivatives
*ENANTIOSELECTIVE catalysis
*CARBOXYLIC acid derivatives

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