Biocatalytic Approach for the Total Synthesis of (-)-Malyngolide and Its C(5)-Epimer.

Authors :: Srivastava, Nikhil
Subba Reddy, Basi V.
Source :: Helvetica Chimica Acta. Apr2016, Vol. 99 Issue 4, p267-272. 6p.
Publication Year :: 2016
Abstract: An enzymatic approach has been successfully utilized in the total synthesis of (-)-malyngolide and its C(5)-epimer. The required configuration was established by an enzymatic kinetic resolution and Sharpless asymmetric dihydroxylation. [ABSTRACT FROM AUTHOR]

Subjects :: *ENZYMES
*EPIMERIZATION
*CHEMICAL processes
*HYDROXYLATION
*CHEMICAL reactions

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