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Occurrence of papillomavirus structural antigens in oral papillomas and leukoplakias.
- Source :
-
Journal of Oral Pathology . Apr84, Vol. 13 Issue 2, p155-165. 11p. - Publication Year :
- 1984
-
Abstract
- Six oral papillomas and 7 oral leukoplakias were studied with genus-specific antibodies against detergent-disrupted papillomaviruses. Indirect immunofuorescence staining was applied to frozen sections. Distinct nuclear staining of superficial keratinocytes was seen in 5 of 6 oral papillomas, 2 of 5 homogenous leukoplakias, and in 2 cases of nodular leukoplakia, one of these showing transition into an invasive carcinoma. Papillomavirus antibodies offer a new way to detect and localize papillomaviruses in opithelial hyperplasias. The relevance of the immunomorphological identification of papillomavirus-associataed antigens is discussed with special reference to the molecular hybridization technique. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PAPILLOMAVIRUSES
*ANTIGENS
*LEUKOPLAKIA
*KERATINOCYTES
Subjects
Details
- Language :
- English
- ISSN :
- 03009777
- Volume :
- 13
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Oral Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 11503086
- Full Text :
- https://doi.org/10.1111/j.1600-0714.1984.tb01412.x