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A portable paper-based microfluidic platform for multiplexed electrochemical detection of human immunodeficiency virus and hepatitis C virus antibodies in serum.
- Source :
-
Biomicrofluidics . 2016, Vol. 10 Issue 2, p1-10. 10p. - Publication Year :
- 2016
-
Abstract
- This paper presents a portable paper-based microfluidic platform for multiplexed electrochemical detection of antibody markers of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in serum samples. To our best knowledge, this is the first paper-based electrochemical immunosensing platform, with multiplexing and telemedicine capabilities, for diagnosing HIV/HCV co-infection. The platform consists of an electrochemical microfluidic paper-based immunosensor array (E-μPIA) and a handheld multi-channel potentiostat, and is capable of performing enzyme-linked immunosorbent assays simultaneously on eight samples within 20 min (using a prepared E-μPIA). The multiplexing feature of the platform allows it to produce multiple measurement data for HIV and HCV markers from a single run, and its wireless communication module can transmit the results to a remote site for telemedicine. The unique integration of paper-based microfluidics and mobile instrumentation renders our platform portable, low-cost, user-friendly, and high-throughput. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19321058
- Volume :
- 10
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Biomicrofluidics
- Publication Type :
- Academic Journal
- Accession number :
- 115096502
- Full Text :
- https://doi.org/10.1063/1.4945311