A step toward simplified detection of serum albumin on SDS-PAGE using an environment-sensitive flavone sensor.

In this study, we report a series of novel flavone-based sensors that exhibit a superior fluorescence response when interacting with serum albumin in real serum samples and in acrylamide gels. The detection limit of probe 4 for serum albumin solution is 0.09 μg mL−1, and the detectable volume for monkey serum reaches as low as 0.03 μL. [ABSTRACT FROM AUTHOR]