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You Are What You Eat: Linking Metabolic Asymmetry and Cell Fate Choice.

Authors :
Landskron, Lisa
Knoblich, Juergen A.
Source :
Developmental Cell. May2016, Vol. 37 Issue 3, p206-208. 3p.
Publication Year :
2016

Abstract

To defend against pathogens, activated immune cells must rapidly produce diverse lymphocyte subtypes. In a recent report in Nature , Verbist et al. (2016) describe how a regulatory loop acting between metabolic and transcriptional programs, centered around the asymmetric cell division machinery and the proto-oncogene c-Myc, establishes distinct T cell fates. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*CELL metabolism
*CELL determination
*PATHOGENIC microorganisms
*CELLULAR immunity
*LYMPHOCYTES
*TRANSCRIPTION factors

Details

Language :
English
ISSN :
15345807
Volume :
37
Issue :
3
Database :
Academic Search Index
Journal :
Developmental Cell
Publication Type :
Academic Journal
Accession number :
115218050
Full Text :
https://doi.org/10.1016/j.devcel.2016.04.017
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