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Host-guest interaction of rotaxane assembly through selective detection of ferric ion: Insight into hemin sensing and switching with sodium ascorbate.
- Source :
-
Dyes & Pigments . Aug2016, Vol. 131, p49-59. 11p. - Publication Year :
- 2016
-
Abstract
- A mechanically interlocked host rotaxane was synthesized by incorporation of tetraphenylethylene and phenanthroimidazole units in the axle to exhibit significant emission bands and demonstrate host-guest interactions via its topologically constrained cavity, and thus to induce a significant and selective fluorescence quenching of rotaxane towards ferric ion (Fe 3+ ). The quenching efficiencies of rotaxane with both ferric ion (Fe 3+ ) and bio-molecular Hemin (containing ferric ion) were investigated to compare the sensitivities of rotaxane for ferric ion and bio-molecular Hemin. The present study could probe host-guest interactions of rotaxane with ferric ion (Fe 3+ ) and Hemin as well as monitoring the biological conversion of Hemin to Heme in presence of sodium ascorbate (as a reducing agent), where the reduced non-toxic Heme could be generated from the toxic form of Hemin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01437208
- Volume :
- 131
- Database :
- Academic Search Index
- Journal :
- Dyes & Pigments
- Publication Type :
- Academic Journal
- Accession number :
- 115368116
- Full Text :
- https://doi.org/10.1016/j.dyepig.2016.03.049