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The use of polymer-based nanoparticles and nanostructured materials in treatment and diagnosis of cardiovascular diseases: Recent advances and emerging designs.
- Source :
-
Progress in Polymer Science . Jun2016, Vol. 57, p153-178. 26p. - Publication Year :
- 2016
-
Abstract
- This review summarizes important advances in polymer-based nanotechnologies for the treatment and diagnosis of cardiovascular diseases, focusing on nanoparticles and nanostructured materials/devices. The current state of the art and design parameters are discussed with the aim of providing a source of information that can aid in the development of new treatments by bridging between materials development, preclinical, and clinical trials. This is highly relevant as cardiovascular diseases remain a leading cause of death worldwide and as current treatments burden the healthcare systems with great costs. Different strategies, from targeting theranostic nanocarriers, to dual-drug depot systems, injectable cell scaffolds, and LDL acceptors are treated. The review ends with a concluding outlook on the possibilities and challenges presented to polymer-based nanotechnologies in cardiovascular disease therapy. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00796700
- Volume :
- 57
- Database :
- Academic Search Index
- Journal :
- Progress in Polymer Science
- Publication Type :
- Academic Journal
- Accession number :
- 115368935
- Full Text :
- https://doi.org/10.1016/j.progpolymsci.2016.01.002