Nitro-polyols via Pyridine-Promoted C=C Cleavage of 2-Nitroglycals. Application to the Synthesis of (-)-Hyacinthacine A1.

The article discusses research being done on the pharmaceutical importance of iminosugars. It references a study published in the 2016 issue of "Organic Letters," by Professor Xin-Shan Ye et al., which examined the adoption of a method for the chemical synthesis of nitro-polyols and their applications in the iminosugar synthesis. The variables considered include iminosugars as immunosuppressive agents, the chirality of glycals and the nitration of glucal and scission of the carbon-carbon bond.