Traditional Persian medicine (TPM) approach to psoriasis treatment.

Objectives: Psoriasis is a chronic inflammatory skin disease with a recurrent nature. Treatment of this disorder takes long due to patients' non-compliance and its severe side effects. Traditional Persian medicine (TPM) is an ancient medical system dating back to 6000 years ago, originating from Persian regions, the most important of which was Iran. This research is designated to determine the treatments and natural remedies that ancient Iranian scientists have used to treat lesions described with symptoms close to common modern psoriasis. One of the complexities of using TPM known diseases is describing and finding the current medical problems in the traditional medicine manuscripts. Materials and Methods: In this study, using TPM treatment books such as, Tebb-e- akbary, Exir-e-azam, Moalejat-e-Aghili and Alhavy, the symptoms of psoriasis were matched with diseases that were described with similar symptoms as psoriasis, such as Bahaq-e- asvad, baras-e- asvad, saafe, Guba. Search for herbal remedies was done using the keywords found in the main TPM manuscripts, especially in remedy (Mofradat) and treatment (Moalejat) TPM books. Herbs mentioned for different TPM keywords were investigated for effects on psoriasis. Searches were performed in the digital libraries and databases with the keywords including "Psoriasis", "keratinocytes", "inflammation" and "Skin disorder" without time limit. Results: According to Iranian humoral medical system, we introduced categorized lists of causes of diseases and the treatments used including mineral and herbal remedies and combinations used orally and topically and advises regarding lifestyle modification. [ABSTRACT FROM AUTHOR]