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Aza-Henry Reactions on C-Alkyl Substituted Aldimines.
- Source :
-
Molecules . Jun2016, Vol. 21 Issue 6, p723. 11p. 7 Diagrams, 3 Charts. - Publication Year :
- 2016
-
Abstract
- The reactivity of C-CH3 substituted N-protected aldimines in aza-Henry addition reactions was compared with that of the analogous trifluoromethylated compounds. C-Alkyl aldimines easily reacted with nitro alkanes under solvent-free conditions and in the absence of catalyst, despite being worse electrophiles than C-CF3 aldimines, they gave the aza-Henry addition only when ZrCl4 was added. The presence of a bulky group on the imine carbon deeply influenced the reactivity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 21
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 115909147
- Full Text :
- https://doi.org/10.3390/molecules21060723