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The enhancement effect of gold nanoparticles as a surface modifier on DNA sensor sensitivity

Authors :
Liu, Tao
Tang, Ji’an
Jiang, Long
Source :
Biochemical & Biophysical Research Communications. Jan2004, Vol. 313 Issue 1, p3. 5p.
Publication Year :
2004

Abstract

The enhancement of a single strain DNA probe linked to the sensor surface is of crucial importance in DNA molecule recognition. By means of nanogold modification of the sensor surface in addition to the nanogold amplifier, DNA detection sensitivity higher than 10−16 mol/L was obtained in a Quartz Crystal microbalance (QCM) system, much higher than the ordinary QCM sensor without surface modification by nanogold. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0006291X
Volume :
313
Issue :
1
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
11609930
Full Text :
https://doi.org/10.1016/j.bbrc.2003.11.098