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IL-1,IL-6,IL-8 与胃癌的关系.

Authors :
赵志威
姜涛
张哲男
侯国伟
王宁
朴大勋
Source :
Progress in Modern Biomedicine. Mar2015, Vol. 15 Issue 8, p1420-1591. 4p.
Publication Year :
2015

Abstract

Gastric cancer is one of the common malignant tumors. It has a higher morbidity than other tumors and its death toll accounts for a quarter. There are nearly 400,000 newly increased patients per year, but the early diagnostic rate is lower than 20%. So gastric cancer has become one of the most serious diseases that endanger our healthy. Interleukins, as the interaction lymphatic factors between white blood cells and immune cells, play an important role in mediating the activation, proliferation and differentiation of the T and B cells, as well as the inflammatory response. In recent years, more and more scholars found that, they have an intimate contact with the occurrence and development of tumor. So far, 29 kinds of interleukins have been discovered and have been named IL-1~IL-29, they bear the corresponding mission respectively. A large number of experiments and literature at home and abroad showed that interleukin-1, 6, 8 have a close relationship with the gastric cancer. It puts forward a new idea for the early diagnosis and treatment, and then improve the early diagnostic rate and treatment of gastric cancer. In this paper, the sources, molecular structure and receptor of IL-1, IL-6, IL-8 are summarized briefly, and the biological characteristics and the relation with gastric cancer are also described. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
16736273
Volume :
15
Issue :
8
Database :
Academic Search Index
Journal :
Progress in Modern Biomedicine
Publication Type :
Academic Journal
Accession number :
116287899
Full Text :
https://doi.org/10.13241/j.cnki.pmb.2015.08.046