运动障碍病脑深部电刺激手术的并发症分析.

Objective To analyze the surgical complications of deep brain stimulation ( DBS) for movement disorders ( MD) to explore its reason and prevention and treatment measures .Methods 615 patients with MD were received 1008 DBS electrodes.Of 615 patients, 222 received unilateral DBS surgery and 393 received bilateral DBS surgery .Of 615 patients, 566 were medically refractory Parkinson disease, 18 essential tremor, 11 dystonia, 7 cervical distonia, 9 tourette, 2 Meige syndrome and 2 other hyperkinetic movement disorders .The surgical procedure or hardware failure related complications were analyzed retrospectively .Results 615 patients were followed up for 1-3 years.Five severe intraoperative adverse events included intracerebral hemorrhage in 4 (0.7%) and acute edema in 1 ( 0.2%) .Hardware-related complications requiring surgical revision included wound infections in 10 patients (1.6%),Subcutaneous effusion around IPG in 10(1.6%),lead malposition and/or migration in 9(1.5%),component fracture in 10(1.6%), hardware discomfort in 1 patient ( 0 .2%) .Conclusions Many operative skills in DBS are associated with postoperative complications .Improving the experience of surgeon can significantly reduce the incidence of surgical complications. [ABSTRACT FROM AUTHOR]