Back to Search
Start Over
Synthesis of hybrid natural product analogues with anti-tumour properties.
- Source :
-
Tetrahedron . Sep2016, Vol. 72 Issue 35, p5433-5443. 11p. - Publication Year :
- 2016
-
Abstract
- High yielding and diastereoselective conjugate addition reactions of a (−)-quinic acid derived enone have provided access to a small library of hybrid analogues of the anti-tumour natural products antheminone A and COTC. The novel compounds were assessed for their antiproliferative activities towards the A549 non-small-cell lung cancer cell line revealing some useful structure-activity relationships. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 72
- Issue :
- 35
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 117158906
- Full Text :
- https://doi.org/10.1016/j.tet.2016.07.033