抗骨质疏松药物治疗老年股骨转子间骨折疗效分析.

Objective To observe the curative effect of anti-osteoporotic drugs on osteoporotic intertrochanteric fractures after internal fixation in the elderly. Methods Fifty-seven elderly patients, who were over 60 years old and diagnosed with osteoporotic intertrochanteric fractures from July 2013 to June 2014 in our hospital, were selected. They were divided into group A (30 cases, with the use of anti-osteoporotic drugs) and group B (27 cases, without the use of anti-osteoporotic drugs). Oral D-Cal and alendronate were administered on the fifth day after the surgery. The healing time of the fracture, complications, Harris hip score, and bone mineral density (BMD) were observed. Results Twenty-six cases in group A and 24 cases in group B were completely followed-up. There was no statistical difference in the fracture healing time and complications (P > 0. 05) between the two groups. After 12 months of surgery, the score of Harris in group A was higher than that in group B,with statistical significance (P < 0. 05). The serum calcium and vitamin D levels was lower in two groups three days after surgery than those before the surgery, with statistical significance (P < 0. 05). After 6 months of the surgery, the serum calcium and vitamin D levels in group A increased comparing to those before the surgery and three days after surgery,with statistical significance (P < 0. 05). BMD in group A and group B was not different in 6 months of the surgery. After 12 months of the surgery, BMD increased in group A, but did not increase in group B, comparing to that before the surgery. Conclusion The use of anti-osteoporotic treatment increases BMD in the elderly patients with osteoporotic intertrochanteric fractures, and obtains better curative effect. [ABSTRACT FROM AUTHOR]