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An environmentally friendly approach to pyrrolo[1,2-a]quinoxalines using oxygen as the oxidant.

Authors :
Wang, Chao
Li, Yun
Zhao, Jianfei
Cheng, Bin
Wang, Huifei
Zhai, Hongbin
Source :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2016, Vol. 57 Issue 35, p3908-3911. 4p.
Publication Year :
2016

Abstract

We have developed an environmentally benign and practical protocol for the synthesis of pyrrolo[1,2- a ]quinoxalines, which represent ubiquitous structural units common to a number of biologically active compounds. This synthetic system features simple operation and using clean oxidant, as well as mild reaction conditions. Both aromatic and aliphatic aldehydes can be used for the reaction and the products were obtained in good to excellent yields. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00404039
Volume :
57
Issue :
35
Database :
Academic Search Index
Journal :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :
Academic Journal
Accession number :
117292233
Full Text :
https://doi.org/10.1016/j.tetlet.2016.07.041