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The other side of the coin: Leveraging Epstein-Barr virus in research and therapy.

Authors :
Yu, Fenggang
Tan, Wei Jian
Lu, Yanan
MacAry, Paul A.
Loh, Kwok Seng
Source :
Oral Oncology. Sep2016, Vol. 60, p112-117. 6p.
Publication Year :
2016

Abstract

Epstein-Barr virus is (EBV) a ubiquitous virus prevalent in 90% of the human population. Transmitted through infected saliva, EBV is the causative agent of infectious mononucleosis (IM) and is further implicated in malignancies of lymphoid and epithelial origins. In the past few decades, research efforts primarily focused on dissecting the mechanism of EBV-induced oncogenesis. Here, we present an alternate facet of the oncovirus EBV, on its applications in research and therapy. Finally, discussions on the prospective utilization of EBV in nasopharyngeal carcinoma (NPC) diagnosis and therapy will also be presented. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13688375
Volume :
60
Database :
Academic Search Index
Journal :
Oral Oncology
Publication Type :
Academic Journal
Accession number :
117441822
Full Text :
https://doi.org/10.1016/j.oraloncology.2016.07.010