Mecanisme de rezistenţă a tulpinilor de Mycobacterium tuberculosis.

Cases of multidrug resistant tuberculosis are on the rise in many regions; therefore prevention programs are fundamental to reduce the incidence of tuberculosis. Knowledge of the risk factors and understanding of the mechanisms which underlie the acquired resistance of Mycobacterium tuberculosis strains can contribute to the implementation of prevention and control strategies. This paper reviews the main risk factors and mechanisms involved in the acquisition of resistance to first and second line anti-tuberculosis drugs. [ABSTRACT FROM AUTHOR]