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Treatment of Pigmented Basal Cell Carcinoma with 3 mm Surgical Margin in Asians.
- Source :
-
BioMed Research International . 8/29/2016, Vol. 2016, p1-6. 6p. - Publication Year :
- 2016
-
Abstract
- Background. In Asians, most basal cell carcinomas (BCCs) are pigmented with clear borders. The consensus of 4 mm surgical margin for BCC largely depends on studies in nonpigmented BCCs in Caucasians. However, little is known about recurrences of pigmented BCCs with a narrower surgical margin. We aimed to investigate 5-year recurrence of BCCs, either pigmented or nonpigmented, in Taiwanese with 3 mm surgical margin. Materials and Methods. 143 patients with BCC (M/F = 66/77, average 64 years) were confirmed pathologically from 2002 to 2013. Based on the pathological margin (>1 mm, ≤1 mm, and involved), patients were categorized into the complete excision group (n=77), histology with close proximity group (n=43), and unclear surgical margin group (n=23). Results. Among 143 cases, 105 were pigmented. With standard 3 mm excision, there were 7 recurrences, with 6 of them from nonpigmented BCC group. Logistic regression showed that pigmentation was associated with lower recurrence. Interestingly, 5-year recurrence of completely excised and histology with close proximity BCC (0/77 versus 1/43) was not different statistically. Conclusions. A 3 mm surgical margin is adequate for pigmented BCC. A “wait and see” approach rather than further wide excision is appropriate for BCC with <1 mm free margin. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AGE distribution
*CANCER relapse
*ASIANS
*BASAL cell carcinoma
*CHI-squared test
*CONFIDENCE intervals
*PROBABILITY theory
*RESEARCH funding
*SEX distribution
*T-test (Statistics)
*LOGISTIC regression analysis
*ANIMAL coloration
*RETROSPECTIVE studies
*SURGICAL site
*DESCRIPTIVE statistics
*SURGERY
*DIAGNOSIS
*CANCER risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2016
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 117744668
- Full Text :
- https://doi.org/10.1155/2016/7682917